HIV postexposure prophylaxis resources
July 1, 1999 2 minutes read
HIV postexposure prophylaxis resources
The HIV Postexposure Prophylaxis (PEP) Registry, in existence since October 1996, closed to new registrants Dec. 31, 1998. Prelimi nary results show that health care workers for whom HIV PEP is prescribed report widely recognized toxicities from those treatments, suggesting that careful counseling regarding drug toxicity may be necessary to improve PEP compliance among exposed HCWs.
Hospital Employee Health will bring you a full report on the PEP Registry’s findings as soon as the data become available. In the meantime, the following information and contacts are available:
• Health care provider questions on HIV PEP management. 24-hour PEPline: (888) 448-4911.
• Information for Health-Care Workers: Occupational Exposure to HIV brochure (can be copied). 24-hour National Prevention Information Network: (800) 458-5231; CDC Web site: www.cdc.gov/ncidod/hip/faq.htm.
• Centers for Disease Control and Preven tion. Public Health Service guidelines for the management of health-care worker exposures to HIV and recommendations for postexposure prophylaxis. MMWR 1998; 47(No. RR-7):1-33. Single copies (free) available from the CDC National AIDS Clearinghouse: (800) 458-5231; multiple copies: Superintendent of Documents, U.S. Government Printing Office, (202) 512-1800; or CDC Web site: www.cdc.gov/ncidod/hip/ BLOOD/HIV_PEP.HTM.
• Information on hepatitis exposures. CDC Hepatitis Information Line (9 a.m.-5 p.m. EST weekdays): (888) 443-7232.
• Drug information or reporting adverse events (all phone numbers have daytime hours and after-hours emergency call coverage).
— nelfinavir, Agouron Pharmaceuticals, (888) 847-2237.
— nevirapine, Boehringer Ingelheim Pharmaceuticals, (800) 542-6257.
— didanosine, stavudine, Bristol-Myers Squibb, (800) 426-7644.
— zidovudine, lamivudine, Glaxo Wellcome, (888) TALK2GW.
— saquinavir, zalcitabine, Hoffmann-LaRoche, (800) 526-6367.
— indinavir, Merck & Co., (800) 927-8888.
• Reporting adverse events. FDA MedWatch: (800) 933-1088.
• Pregnancy antiretroviral surveillance program. Pregnancy exposures to an antiretroviral product — 24-hour Antiretroviral Pregnancy Registry: (800) 258-4263.
• Other HIV PEP surveillance programs. CDC National Surveillance System for Hospital Health Care Workers. Currently 23 hospitals use provided software for tracking occupational HIV exposures in exchange for exposure information from those tracked. (404) 639-6425, 9 a.m.-5 p.m. EST weekdays.
Source: HIV Postexposure Prophylaxis Registry, Wilmington, NC.
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