Another treatment option for smallpox reactions
Another drug besides vaccinia immune globulin (VIG) that may be used to treat certain serious smallpox vaccine reactions is the antiviral drug cidofovir (Vistide). Here are some of the facts about cidofovir, as provided by the Centers for Disease Control and Prevention in Atlanta:
- Cidofovir currently is licensed for the treatment of CMV retinitis and has demonstrated antiviral activity against poxviruses in vitro and against cowpox and vaccinia viruses in mice.
- However, its use for the treatment of vaccinia adverse reactions is restricted under an Investigational New Drug (IND) protocol. Under the IND, cidofovir would only be used when VIG was not efficacious.
- Renal toxicity is a known adverse reaction to cidofovir.
Another drug besides vaccinia immune globulin (VIG) that may be used to treat certain serious smallpox vaccine reactions is the antiviral drug cidofovir (Vistide).
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