Clinical Brief Notes
June 1, 2016
Researchers may be closer to an Ebola vaccine as two vaccines showed promise in a recent clinical trial (JAMA 2016;315:1610-1623).
Diflucan, which is commonly prescribed to women for yeast infections, may increase the risk for miscarriage. The FDA advises caution in using the drug during pregnancy. (http://1.usa.gov/24C3wRr).
The DPP-4 inhibitors saxagliptin and sitagliptin do not increase the risk for heart failure relative to other diabetes medications (Ann Intern Med published online April 26, 2016. doi:10.7326/M15-2568).
Metformin is still a first-line therapy for type 2 diabetes mellitus as monotherapy or combination therapy because of its safety and beneficial effects, based on the findings of a large meta-analysis (Ann Intern Med published online April 19, 2016. doi: 10.7326/M15-2650).
Researchers make progress on Ebola vaccine and diabetes treatments.
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