In a similar study, tuberculosis treatment for 4 months including a fluoroquinolone was not as effective as standard 6-month therapy, according to three studies published in the Oct. 23 edition of the New England Journal of Medicine. The three regimens included either moxifloxacin or gatifloxacin in nearly 4600 patients, mostly in sub-Saharan Africa, with some patients in India, Asia, and Mexico. None of the treatment regimens met criteria for noninferiority with regard to treatment failure or relapse (N Engl J Med 2014;371:1577-1587, 1588-1598, 1599-1608). While more research is needed, 6 months of treatment remains the gold standard for treatment of tuberculosis.
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