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Women with breast cancer susceptibility gene (BRCA) mutations are at risk for breast and ovarian cancers. Ovarian cancer often escapes early detection because laboratory and imaging screening tools are less effective than those developed for breast cancer. Ovarian cancer is marked with a less-robust five-year survival rate (44%), compared with nearly 90% for breast cancer.
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Although widespread screening mammography has greatly increased the diagnosis of early breast cancer, it has had only a marginal effect on the diagnosis of late-stage tumors and breast cancer mortality.
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The authors concluded that compared to beta-blockers, the risk of angioedema is highest with ACEIs or aliskiren and lowest with ARBs.
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The authors conclude that in a large cohort of older patients with atrial fibrillation, hemorrhage is common during both the first 30 days and subsequent months of warfarin therapy, and is related to risk factors in the CHADS2 score and also to age.
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The first inhibitor of the microsomal triglyceride transport protein (MTP) has been approved for the treatment of homozygous familial hypercholesterolemia (HoFH).
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During family discussions, physicians who believe more strongly that life support should be withdrawn are more likely to present the option of comfort care and describe its benefits.
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CKD: Consistency of GFR and Albuminuria as Risk Predictors; Changing Outcomes for Patients with Chronic Hepatitis C; Is Fructose a Primary Culprit in Obesity?
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An 80-year-old woman with a past history of non-Hodgkins lymphoma (follicular type, stage IIA) developed progressive confusion, unsteady gait, difficulty hearing and weight loss over a 4 month period.
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In this issue: Apixaban approval; new dental clinical practice guideline; apixaban for VTE; aspirin resistance; tamoxifen treatment; and FDA actions.
