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A team from UCSF recently reviewed company documents that were entered into the public record as a result of litigation over the promotion of gabapentin (Neurontin) between 1994 and 1998.
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A medical research unit in the United Kingdom analyzed 18 different strategies for managing patients with suspected deep vein thrombosis (DVT). Using systematic review, meta-analysis and cost effectiveness analysis, they settled on an algorithm based on clinical risk.
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HCV may persist and replicate in the liver and PBMCs of healthy, anti-HCV antibody-positive, serum HCV RNA-negative patients who have persistently normal ALT levels. These patients should be followed up, because they have an ongoing viral infection.
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Antibiotics may improve acute purulent rhinitis at the cost of gastrointestinal upset and rash.
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Tight glucose control has been shown to provide improved outcomes in both Type 1 and Type 2 diabetes (DM2).
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Functional dyspepsia cannot reliably be diagnosed using symptoms alone. Esomeprazole therapy is not effective vs placebo in an 8-week study of endoscopy-negative patients with histories thought to be diagnostic of FD.
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Warfarin remains superior to antiplatelet agents for stroke prevention in patients with AF.
