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The SPARCL study showed that 80 mg per day of atorvastatin reduced the overall incidence of recurrent stroke, and a meta-analysis of several large studies of ACE inhibitors showed a reduction in all stroke types, as well as a reduction in overall cardiovascular mortality.
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A medical research unit in the United Kingdom analyzed 18 different strategies for managing patients with suspected DVT.
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Both nitazoxanide and the investigational anionic polymer, tolevamer, may have efficacy comparable to that of standard therapies in the treatment of CDAD. The addition of rifampin to metronidazole is not superior to treatment with metronidazole alone.
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Aspiration of oropharyngeal secretions is considered one of the mechanisms of development of VAP. In this randomized trial of two oral decontamination medications, the authors show a significant reduction in the incidence of VAP.
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The 2006 guidelines for the management of patients with atrial fibrillation clarify previous recommendations for anticoagulation to prevent other thromboembolic events.
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In ACS patients without persistent ST-segment elevation, there is a strong, consistent, temporal, and dose-related association between bleeding and death.
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In the United States during 2002, asthma accounted for 12.7 million physician visits; 1.9 million emergency department (ED) visits; 484,000 hospitalizations; and 4,261 deaths. The prevalence of asthma in our society has led it to be the eleventh most common diagnosis in the ED. The direct and indirect costs of the disease are estimated to exceed $14 billion annually in the United States alone.
