Primary Care/Hospitalist
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Pioglitazone Improves Fibrosis Scores in Nonalcoholic Steatohepatitis Patients With and Without Diabetes
In a meta-analysis of eight studies (five pioglitazone, three rosiglitazone) involving 516 patients with biopsy-proven nonalcoholic steatohepatitis, pioglitazone was found to improve fibrosis between six and 24 months.
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Can Magnesium Cure Nocturnal Leg Cramps?
A small randomized, double-blind, placebo-controlled trial demonstrated that oral magnesium oxide was not superior to placebo for older adults suffering from nocturnal leg cramps.
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Screening, Anticipatory Guidance Needed to Address Teen Sexual Assault
Teens are more likely to delay medical care and less likely to press charges.
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Minimally Invasive Uterine Fibroid Treatment Underutilized
Use rates particularly low in small and rural hospitals, according to a recent report.
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More Research Needed on Benefits, Harms of Screening Pelvic Exams
According to one expert: “At this time, there simply is not enough evidence to determine the benefits and harms of using pelvic exams to screen for conditions other than cervical cancer, chlamydia, and gonorrhea.”
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Check Birth Control Start After Ulipristal Acetate
Results of recent study lead manufacturer of important drug to update its recommendations.
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New Estimates Show Drop in Annual HIV Infections
Still, much work remains as agencies push for wider access to key resources.
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Implement Resources for Immediate Postpartum LARC to Cut Unintended Pregnancy
Many women engage in unprotected sex before six-week postpartum visit.
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High-sensitivity Cardiac Troponin
In patients with new-onset chest pain without ECG evidence of an ST-elevation myocardial infarction, conversion to the use of a high-sensitivity troponin T assay with three-hour retesting in three hospitals was compared to maintaining the fourth-generation troponin T assay with six-hour retesting in three other hospitals. The use of high-sensitivity troponin T resulted in lower ED length of stay and costs, without increasing the use of coronary angiography or stress testing. -
Hyperoxia in ICU Patients May Cause Harm
Patients randomized to maintain oxygen saturation between 94-98% experienced better outcomes than patients allowed to receive partial pressure of oxygen > 150 mmHg.