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Effective cardiopulmonary resuscitation (CPR) is partly dependent on the adequacy of manual chest compressions, but they are limited by interruptions and less than ideal conditions such as during transport. Mechanical chest compression devices have been developed that improve organ perfusion vs manual compressions in experimental studies, but there is little evidence of their clinical effectiveness and safety compared to manual compressions.
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A systematic review and meta-analysis found that the healthcare-associated pneumonia concept was based on low-quality evidence confounded by publication bias and does not accurately identify antibiotic-resistant pathogens.
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Implementation of an evidence-based extubation-readiness bundle was associated with a decrease in mechanical ventilation days and pneumonia in brain-injured patients.
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At this time, ventricular fibrillation (VF) early after acute myocardial infarction (MI) is not an indication alone for an implantable cardioverter-defibrillator (ICD) therapy. However, there is concern that despite the efficacy of mechanical and pharmacological therapy for acute MI, the risk of subsequent sudden cardiac death (SCD) in patients with VF complicating acute MI may be higher and the guidelines should be revisited.
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ACEP, AAP, and several other prominent pediatric and critical care organizations have endorsed the practice of offering parents the choice about being present during invasive procedures and resuscitations.
The majority of the literature supports providing the parents the choice to be able to remain with their children during procedures, including resuscitative efforts.
There have also been psychological benefits with family members who remained present during resuscitations by lowering their anxiety and depression scores, having fewer disturbing memories, and lowering degrees of intrusive imagery and post-traumatic avoidance behavior.
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In a multicenter study of patients with an episode of first proximal deep venous thrombosis, elastic compression stocking use did not prevent the development of post-thrombotic syndrome.
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In a retrospective cohort study, elderly patients who were prescribed calcium-channel blockers (CCBs) with clarithromycin were at increased risk for developing acute kidney injury.