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Clinical Briefs

In this section: comparing GLP-1 agonists; weighing two treatments for extended venous thromboembolism; and considering fracture risks possibly associated with inhaled corticosteroids.

Ibalizumab-uiyk Injection (Trogarzo)

Ibalizumab-uiyk, in combination with other antiretrovirals, is indicated for the treatment of HIV-1 in heavily treatment-experienced adults with multidrug-resistant HIV infections failing their current regimens.

After Myocardial Infarction, Increased Risk for Ischemic Stroke Persists for 12 Weeks

This study establishes that the elevated short-term risk of stroke extends beyond 30 days and remains elevated for up to 12 weeks following acute myocardial infarction.

Stroke Risk in Atrial Fibrillation: A Moving Target?

An investigation of patients in a national database with atrial fibrillation, no comorbidities, and not on aspirin or anticoagulants showed that the clinical features that make up the CHA₂DS₂-VASc score change over time and can increase a patient’s risk for stroke, which could affect therapy decisions. Thus, the CHA₂DS₂-VASc score should be reassessed periodically and appropriate therapeutic actions taken promptly.

Elderly May Not Benefit From Statins for Primary Prevention

In an examination of the data from the much-publicized Systolic Blood Pressure Intervention Trial (SPRINT), the author found no benefit of statin therapy for primary prevention of cardiovascular events or all-cause mortality.

Research Examines Use of Tenofovir Gel in Women

As HIV infection continues to be a major public health issue, tenofovir gel is being researched as a topical pre-exposure prophylaxis strategy for HIV prevention in women.

Provider Training May Boost Rates of HPV Vaccination

Results of a recent study indicate a training intervention to aid provider communication about HPV vaccines with teen patients and their parents increased initiation and completion of the vaccine series.

Get up to Speed in Addressing Urinary Tract Infections

Research presented at the 2017 annual meeting of the Infectious Diseases Society of America indicates that women at risk of urinary tract infection (UTI) who increased their water intake by drinking an additional three pints of water a day were almost half as likely to get infections as women who did not.

Prevalence of HSV-2 Is Falling, Data Show

Two of the most common viruses, herpes simplex virus-1 (HSV-1) and herpes simplex virus-2 (HSV-2), are steadily declining in the U.S. population.

No Link Found Between Progestin-only Birth Control Methods and Depression

Results of a new review of all available data indicate no evidence to support a link between progestin-only birth control and depression.