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Statin use among cancer patients with diverse malignancies is associated with reduced cancer-related mortality. The mechanism is plausible since statins inhibit cholesterol synthesis, which reduces the pool of compounds necessary in cellular proliferation and maintenance of critical cellular functions, such as membrane integrity, signaling, protein synthesis, and cell cycle progression. Prospective clinical trials are warranted.
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Omalizumab for Asthma in Real Life; Tenofovir: New Hope for Hepatitis B Patients; H. pylori: Frequency of Recurrence After Successful Eradication
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The first in a new class of drugs has been approved by the FDA for the treatment of diabetes mellitus. This new class of drugs decreases the renal threshold for glucose excretion by inhibiting the sodium-glucose co-transporter 2 (SGLT2), thus increasing renal clearance of glucose. Canagliflozin is licensed from Mitsubishi Tanabe Pharma Corporation and marketed by Janssen Pharmaceuticals as Invokana.
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A new Agency for Healthcare Research and Quality (AHRQ) review of available evidence reveals that women who have problematic irregular or heavy cyclic menstrual bleeding have several safe and effective nonsurgical treatment options.1
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In a decision more than 10 years in the making, a U.S. Federal District judge ruled April 5, 2013, that the Food and Drug Administration (FDA) must lift age and point-of-sale restrictions on Plan B One-Step emergency contraception (EC) within 30 days.
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Results of a just-published study indicate a possible method to predict when a woman will have her final menstrual period.1 Such findings might be helpful in aiding women and providers in combatting potential bone loss and cardiovascular risk associated with onset of menopause.
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Women over age 40 might underestimate their need for effective birth control; however, despite declining fertility, such women can be at risk for unintended pregnancy.
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With the recent Food and Drug Administration approval of Quartette, a new extended regimen oral contraceptive (OC) from Teva Pharmaceuticals of North Wales, PA, providers have more options to present to women considering this form of birth control.
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While teen pregnancies are declining in the United States, the nation still leads the worlds high-income countries in live teen births, points out a recent Centers for Disease Control and Prevention (CDC) Public Health Grand Rounds session.1
