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Rheumatologic and autoimmune disease patients often present with very complex manifestations that can be confusing and challenging to accurately diagnose. Clinicians increasingly depend on both common and arcane laboratory testing to facilitate arriving at a confident final diagnosis, even though most diagnoses are made through thorough history taking and careful physical examination.
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Evidence-based updates in primary care medicine By Louis Kuritzky, MD
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The ECG shown above was obtained from an acutely ill but alert and hemodynamically stable patient. How certain are you that the rhythm is ventricular tachycardia (VT)? Might there be another explanation if the patient in question was a young adult with renal disease and diabetes?
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The distress felt by patients with recurring bouts of Clostridium difficile diarrhea is so acute that they welcome the opportunity to accept anothers feces to bring them back to baseline. There have been more than 30 publications on the topic since it was first introduced in 1958,1 most of them in the last 10 years.
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Risks and Benefits of an Extended 10-year Tamoxifen Regimen for Breast Cancer; Is There More Pro than Con in Probiotics in Critically Ill Adults?; The ASH Position Paper on Orthostatic Hypotension
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Chelation therapy for cardiovascular disease; statins and kidney injuries; chlorthalidone for hypertension; and FDA actions.
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The FDA has approved a fixed combination of doxylamine succinate and pyridoxine for the treatment of nausea and vomiting due to pregnancy. This is a reintroduction of a product widely used between 1956 and 1983.
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Use of an intravenous chelation regimen with disodium EDTA, compared with placebo, modestly reduced the risk of adverse cardiovascular outcomes in stable patients with a history of myocardial infarction (MI). These results do not support the routine use of chelation therapy for treatment of patients who have had a prior MI.
