OB/GYN Clinical Alert
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Women Who Experienced Miscarriage or Stillbirth Early in Life Have an Increased Risk of Stroke in Later Life
Investigators performed a comprehensive literature search and meta-analysis of 16 cohort studies and two case-control studies that reviewed the records of 7,808,521 women who experienced complications around pregnancy to determine the subsequent risk of stroke and determined that women who had experienced miscarriage or stillbirth were at a higher risk of future stroke.
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Antihypertensive Therapy for Mild Chronic Hypertension in Pregnant Women
Antihypertensive treatment of mild chronic hypertension in pregnant women was associated with reduced risk of preeclampsia with severe features, medically indicated preterm birth at < 35 weeks’ gestation, placental abruption, and fetal or neonatal demise compared to no treatment.
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Does Bilateral Salpingo-Oophorectomy at the Time of Benign Hysterectomy Reduce Ovarian Cancer Risk?
In this retrospective cohort study of 195,282 women who underwent benign hysterectomy with or without bilateral salpingo-oophorectomy (BSO), the group who underwent BSO had a decreased ovarian cancer incidence (hazard ratio, 0.23; 95% confidence interval, 0.14-0.38) at 16 years of follow-up compared to those who retained their ovaries.
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Age and Risk of Sterilization Regret: Analysis of a Contemporary Dataset
In this retrospective analysis of the 2015-2017 and 2017-2019 National Survey of Family Growth female respondent files, women younger than 30 years of age were more likely to experience sterilization regret compared to women older than 30 years of age. As women got older, sterilization regret decreased, and no other demographic or clinical factors, including race, parity, educational attainment, or medical reasons for sterilization, were associated with regret.
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Does Heavy Menstrual Bleeding Cause More IUD Expulsions?
In this retrospective cohort study of 6,203 women, there was no difference in expulsion rates between individuals using the levonorgestrel intrauterine device (IUD) for heavy menstrual bleeding and those using it for contraception, using a protocol where the IUD for patients with heavy menstrual bleeding was inserted only after bleeding had ceased or lessened.
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HPV Vaccination in Adolescence Prevents Cancer More than 10 Years Later
This long-term follow-up study of three cluster-randomized trials of human papillomavirus (HPV) vaccination evaluated cancer protection over up to 11 years of follow-up. During this time, 17 HPV-positive cancers were identified in the unvaccinated group, and 0 were identified in the vaccinated group, indicating 100% vaccine efficacy at preventing HPV-associated cancers.
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Women’s Experiences of Racism and Reproductive Health
Black adult women in three cities in the United States describe using a range of actions to protect themselves against racism in the reproductive healthcare space.
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Pregnancy Outcomes in Women with CVD
Pregnant patients with severe cardiac disease experience a higher risk of adverse cardiac outcomes compared to those with mild to moderate disease.
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Sickle Cell Disease During Pregnancy
Sickle cell disease (SCD) is the most commonly inherited autosomal recessive genetic hemoglobinopathy in the United States. People with SCD account for only 0.1% of all deliveries, but approximately 1% of maternal deaths, a 10-fold increased risk.
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Are Urine Dipsticks Accurate for Preeclampsia Diagnosis?
This systematic review found that urine dipsticks of 1+ protein had a sensitivity of only 68% for the diagnosis of preeclampsia (95% confidence interval, 0.57-0.77), which was considered poor. Performance improved at thresholds of 2+ and 3+ protein.