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Building on the results of previous pilot studies from their laboratory and a meta-analysis that showed a tendency toward improved mortality in critically-ill patients following selenium administration, Angstwurm and colleagues used a randomized, placebo-controlled multi-center trial to determine whether intravenous administration of selenium could improve outcomes in severe sepsis and septic shock.
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In the institution in which this study took place, an audit revealed that adherence to 9 ICU protocols ranged from 62% to 77%. The protocols focused on a variety of patient care needs including sedation/analgesia, DVT prophylaxis, enteral nutrition, insulin administration, skin care, stress ulcer prophylaxis, and ventilator weaning.
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IBS-Drug Treatment Pulled, CV Side Effects; Drug Combo Better for Migraine Treatment; Pergolide Off the Market, Heart Disease Risk; Hormone Treatment, Does Timing Matter?; FDA Actions
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In a group of smokers who were hospitalized with cardiac symptoms, a combination of 12 weeks of behavior modification counseling plus pharmacotherapy resulted in higher tobacco abstinence rates, lower re-hospitalization rates, and markedly reduced mortality rates compared with usual care over two years of follow-up.
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When compared to The Zone, Ornish, or LEARN diets, the very low carbohydrate diet (Atkins), showed that premenopausal, overweight, and obese women lost more weight and had the most beneficial metabolic effects at 12 months.
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The FDA has approved a new oral tyrosine kinase inhibitor with potent, reversible, selective dual inhibition of epidermal growth factor receptor (EGFR) and ErbB2 kinases.
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Recommended periodic preventive services are more likely to be performed through a scheduled screening physical examination or other dedicated preventive visits.
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Because of the high cardiovascular risk associated with prehypertension, both lifestyle and pharmacological interventions should be vigorously utilized to prevent its progression to full-blown hypertension with its associated higher rates of both morbidity and mortality.
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Risk factors for atrial fibrillation (AF) most prominently include age, hypertension, diabetes, valvular disease, and heart failure.
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