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This multicenter, randomized, double-blind, placebo-controlled trial finds that early initiation of low-dose, prolonged glucocorticosteroid therapy for ARDS results in improved lung injury scores and a greater likelihood of successful extubation by day 7.
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Standard 10-day triple therapy for Helicobacter pylori may result in relatively low eradication rates.
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A meta-analysis of 18 studies that have examined the usefulness of procalcitonin measurement in the diagnosis of sepsis finds that the diagnostic performance of this measurement is low and that the test cannot reliably distinguish sepsis from other causes of the systemic inflammatory response syndrome.
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MRI is more sensitive than CT for detecting acute ischemia and can detect acute hemorrhage with equal sensitivity to CT.
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Disturbance of sleep continuity, but not simple sleep deprivation, impairs pain inhibition and increases spontaneous pain.
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GlaxoSmithKline's rosiglitazone (Avandia) will receive a black box warning by the FDA because of concerns over heart failure associated with use of the drug.
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Surgery for a herniated lumbar disc with sciatica does not have a better long-term result than conservative therapy.