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The combination of ampicillin and ceftriaxone was effective in treatment of endocarditis due to E. faecalis. Efficacy was similar for infections involving isolates with and without high-level aminoglycoside resistance.
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In this study of 310,311 veterans aged 65 or older who underwent major noncardiac surgical procedures, 30-day mortality increased 1.6% for every percentage-point decrease in preoperative hematocrit below 39%.
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Methylation of 16S ribosomal RNA (rRNA) has emerged as an important mechanism of resistance to aminoglycosides in pathogens including Enterobacteriaceae and non-fermenters including Pseudomonas aeruginosa and Acinetobacter species.
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In this paper, Hart and colleagues report the results of a meta-analysis of antithrombotic therapy in patients with nonvalvular atrial fibrillation (NVAF).
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This issue of Emergency Medicine Reports is devoted to increasing your understanding of these measures and the role they will play in your practice.
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Several years ago, the PROWESS trial demonstrated a mortality benefit for drotrecogin alfa [activated] (DrotAA; APC) in patients with severe sepsis, and that this benefit was most pronounced in those at high risk of death (ie, APACHE score > 25 or multi-organ dysfunction).
