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In a longitudinal population-based study, metformin use was associated with an increased incidence of low thyroid-stimulating hormone (TSH) levels in patients with treated hypothyroidism.
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Based on a recent systematic review of the literature, clinical guidelines were developed by the American Association of Blood Banks with the goal of providing platelet transfusion thresholds for adult patients in common clinical scenarios.
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In this study of administrative data from patients admitted to 421 U.S. hospitals with acute chronic obstructive pulmonary disease (COPD) exacerbations, 41% received long-acting bronchodilators, which are not recommended in this setting. Comparison with patients who did not receive the long-acting agents showed no evidence for clinical or economic benefit from their use.
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Although studies in animals and preliminary reports in patients with ARDS suggested that statin administration might be beneficial in patients with the syndrome, this multicenter, double-blind clinical trial showed no benefit from simvastatin by any measure examined.
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Venous thromboembolism (VTE) is the third most common cardiovascular condition behind myocardial infarction and stroke, with an incidence rate of about one per 1000 person-years.1,2 Nearly 5% of the population will experience
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This study, done at a tertiary care university hospital here in the U.S., was initiated in an attempt to improve patient safety, conserve a vital resource, and reduce costs a laudable tripartite goal.
