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Prevalence of Rest Tremor in Essential Tremor

Rest tremor is seen in patients with more advanced essential tremor, yet its prevalence varies significantly between patient groups.

Is It Time to Purge Full-Strength Aspirin from the Outpatient Armamentarium?

The current study provides further evidence of a lack of benefit to high-dose maintenance aspirin, along with a suggestion of harm.

Comparative Efficacy and Safety of Blood Pressure-lowering Agents in Adults with Diabetes and Kidney Disease

Although no blood pressure-lowering strategy prolonged survival in adults with diabetes and kidney disease in this meta-analysis, angiotensin-converting enzyme and angiotensin-receptor blockers, alone or in combination, were the most effective pharmacological strategies to prevent the development of end-stage renal disease.

Convexal Subarachnoid Hemorrhage and Amyloid Angiopathy

Cerebral amyloid angiopathy is emerging as a major cause of spontaneous intracerebral hemorrhage in the elderly. The authors of this study undertook a careful review of all of the patients in their database over a 9-year period who had spontaneous convexal subarachnoid hemorrhage, and they performed a careful longitudinal analysis of clinical and neuroimaging data.

Consequences of Intracerebral Hemorrhage in Young Adults

Intracerebral hemorrhage accounts for 10-20% of all strokes in North America and Europe, with an overall incidence of 25 cases per 100,000 population annually. In this study, the authors evaluated the long-term survival and recovery of 268 1-month survivors ages 16-49 years to assess the prognosis of intracerebral hemorrhage in the younger group.

Can Dietary Intervention Delay the Onset of Alzheimer’s Disease?

In a prospective study of an elderly population, moderate adherence to the MIND diet was associated with a 53% reduction in the development of Alzheimer’s disease.

Diagnosing POLG-related Diseases

Mutations of the polymerase-gamma subunit in mitochondrial DNA is a common cause of adult mitochondrial syndromes, such as myopathies, encephalopathies, epilepsy, and ataxias.

Prevalence of Rest Tremor in Essential Tremor

Rest tremor is seen in patients with more advanced essential tremor, yet its prevalence varies significantly between patient groups.

Cerebrospinal Fluid Biomarkers of Neuronal Injury in Mild AD

Cerebrospinal fluid visinin-like protein 1 is a useful marker, along with CSF tau and phospho-tau measurements, to predict brain atrophy and neurodegeneration in patients who carry a clinical diagnosis of Alzheimer’s disease.

Serum and CSF Biomarkers of Brain Injury After Sports-related Concussion

ABSTRACT & COMMENTARY: So far none of the currently measured biomarkers has sufficient sensitivity or specificity to be clinically useful.