Internal Medicine
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Exercise for Depression During Pregnancy
Exercise is associated with better mental outcomes during pregnancy.
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Non-seasonal Major Depressive Disorder: Bright Light Therapy and/or Fluoxetine
In this four-pronged study comparing the effect of bright light treatment, fluoxetine, a combination of these two interventions, and placebo in patients with major depressive disorder, the combination treatment appears the most consistently effective.
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Early Chest CT Can Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.
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Electronic Cigarette and Nicotine Toxicity
MONOGRAPH: Their health effects, potential toxicity with inappropriate consumption, role as a portal to other drugs, and the lack of adequate regulation.
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Does a Sedation Strategy With or Without Daily Interruption Affect Recall of ICU Stay?
Recall of the ICU stay and the type of sedation strategy did not influence the types of memories reported by critically ill patients.
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IV Crystalloids: Is One Better Than the Other?
The decision of which fluid to use is highly variable and predominantly driven by local practice rather than patient or fluid characteristics.
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Clinical Briefs
In this section: revisiting cancer screening recommendations; weighing the benefits of a COPD treatment; and expanding the safe prescribing of metformin.
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Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide (Genvoya)
A complete regimen for the treatment of HIV-1 infections in adults and pediatric patients ≥ 12 years of age.
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Fecal Microbiota Transplantation: Patients Need No Convincing
Fecal microbiota transplantation appears effective in approximately 55-90% of patients with relapsing and refractory Clostridium difficile infection, and will prove a blessing to those who have been in a miserable cycle of recurrent disease.
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Optimal Beta-blocker Dose Post-MI
Investigators from the Outcome of Beta-blocker Therapy After Myocardial Infarction (OBTAIN) study hypothesized that the higher the dose of beta-blocker the lower the mortality.