Internal Medicine
RSSArticles
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Oral Fluconazole During Pregnancy Increases Risk for Spontaneous Abortion
A nationwide cohort study from Denmark found a significantly increased risk of spontaneous abortion associated with oral fluconazole usage. Caution with this medication during pregnancy is advised.
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Human Paraechovirus Encephalitis in Children
Human paraechovirus (HPeV) causes encephalitis and is more common in very young or premature female infants. Affected children commonly present with seizures. Diffusion restriction on MRI in the absence of CSF pleocytosis is seen. Neurodevelopmental sequelae are common after long-term follow up.
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Zika!
Zika virus infection has prompted international emergency responses due to its rapid spread in the Americas and its potential to alter brain development in pre-born children. Even as research progresses, prevention of infection depends on avoiding bites from Aedes mosquitoes.
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Gender Equality in Primary Prevention ICD Benefit
In a propensity-matched study, women who received a primary prevention implantable cardioverter defibrillator had a significant survival advantage, which was similar to that observed among men.
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Permanent Pacemaker After TAVR: A Modifiable Risk?
A study of the latest-generation balloon-expandable valves demonstrates a higher rate of new conduction abnormalities and pacemaker implants than previous models.
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One Procedure or Two? Study Examines Staging for Multi-vessel PCI in NSTEMI
In patients with non-ST elevation myocardial infarction and multi-vessel disease, single-stage percutaneous coronary intervention during the initial procedure is superior to multiple procedures in terms of major adverse cardiovascular and cerebrovascular events and minor bleeding at 1 year.
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Nitrate Therapy Shows Possible Harm in Heart Failure with Preserved Ejection Fraction
In heart failure with preserved ejection fraction, the use of isosorbide mononitrate was associated with a nonsignificant decrease in physical activity level, and no improvement in symptoms or quality of life.
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The Portal of Bacterial Entry in Infective Endocarditis
ABSTRACT & COMMENTARY: A comprehensive, systematic search for the portal of bacterial entry in infective endocarditis is frequently successful.
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Does the Use of Saline vs Buffered Crystalloid Reduce Risk of Acute Kidney Injury in ICU?
The use of a buffered crystalloid compared with saline did not reduce the risk of acute kidney injury in patients receiving crystalloid fluid therapy in the ICU.
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Effects of a Rapid Response System Driven by Real-time Automated Clinical Alerts on Hospital Mortality and Length of Stay
The addition of an automated real-time clinical deterioration alert system to a rapid response system had marginal effects.