Internal Medicine
RSSArticles
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Childhood Head Trauma and Risk of Subsequent Diagnosis of Multiple Sclerosis
A large study that reviewed longitudinally collected data from the national Swedish Patient Register found that head trauma in adolescents was associated with an increased risk of subsequent diagnosis of multiple sclerosis.
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Exploring Cortical Pathology in Multiple Sclerosis With Routine MRI
In this MRI and histopathological study, the investigators showed that cortical T1w/T2w ratio was unrelated to myelin density, but had a strong correlation with dendritic density. Furthermore, abnormal values within the posterior cingulate cortex correlated with impairment in cognitive domains.
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Pitfalls in the Treatment of Seizures Associated With Brain Tumors
In this multicenter, observational study, the authors assessed the prevalence of neuropsychiatric side effects from medications in subjects with tumor-related epilepsy. Levetiracetam was found to have the highest prevalence of such side effects.
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Management of Skin and Soft Tissue Infections
Skin and soft tissue infections are encountered commonly in primary care practices, presenting as a range of disorders, from uncomplicated cellulitis, impetigo, folliculitis, erysipelas, and focal abscesses to necrotizing fasciitis. Each year between 1998-2006 in the United States, there were 650,000 hospital admissions for cellulitis, with estimates of 14.5 million cases annually treated as outpatients, accounting for $3.7 billion in ambulatory care costs.
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Spiritual Healing: A Randomized Clinical Trial
A randomized, controlled trial evaluated the effectiveness of Brazilian energy therapy — Spiritist “passé” — in multiple conditions associated with recovery in cardiovascular inpatients.
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Vitamin D and Colorectal Cancer: The Plot Thickens
In a follow-up study, researchers investigated whether single nucleotide polymorphism (SNP) genotypes in the vitamin D and calcium pathways are associated with the authors’ previous findings that daily intake of 1,000 IU vitamin D3 and/or 1,200 mg calcium did not reduce colorectal adenoma risk. The authors concluded that vitamin D3 supplementation benefits in the prevention of advanced colorectal adenomas may vary depending on vitamin D receptor genotype status.
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Physician Burnout: A Multi-specialty Perspective
Although different specialties address the problem of physician burnout, studies suggest the most effect is gained from organizational interventions.
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Infectious Disease Alert Updates
Travelers Unaware of the Need for Pre-travel Vaccinations; Fecal Microbiota Testing; Newer Guidelines for Influenza Testing This Season
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Chikungunya Locally Acquired in Italy and France
An outbreak of autochthonously acquired chikungunya infection has affected 298 individuals as of early October 2017, while a small outbreak also has occurred in southeastern France.
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Caring for Providers: Mindfulness for Healthcare Practitioners
Preliminary studies show some promise for use of mindfulness interventions in healthcare practitioners, but the time required for training medical providers in these techniques is identified as a limitation to implementation.