Browse Internal Medicine Articles by Topic

Treatment for Spinal Muscular Atrophy

In a randomized, double-blind, sham-controlled study of infants with spinal muscular atrophy (SMA) type 1, nusinersen treatment led to significant improvement in motor milestones and survival without significant adverse reactions. A safety trial of gene therapy for SMA type 1 demonstrated prolonged ventilator-free survival and improved motor milestones with minimal side effects.

What Do You Know About Wound Care?

This article will summarize the salient features of wound care, including demographics of a changing population, fundamental phases of wound healing, advances in therapeutic modalities, and steps family physicians can take to become recognized as certified wound care physicians.

Topical Cannabis for Wound Pain: A Case Series

For three people with continued pain despite conventional treatment for pyoderma gangrenosum, topical cannabis led to statistically significant pain relief for two of them.

Low Serum 25-hydroxyvitamin D and Risk of Frequent Headache

Low vitamin D levels are associated with a range of neurovascular diseases, but little data are available on the association between vitamin D levels and headaches. This retrospective, cross-sectional study showed that low serum vitamin D levels were associated with a higher risk of frequent headaches in middle-aged/elderly Finnish men.

Black seed (Nigella sativa) for Asthma: Minimal Effects

SYNOPSIS: Black seed, crushed, in capsule form, administered to 76 people with asthma in a single-blind, randomized study, showed some minimal improvements in some, but not all, components of spirometry and one serum cytokine after 12 weeks.

Use of Essential Oils as an Alternative Treatment for Depression

The antidepressant effects of essential oils are promising, but more studies in humans beyond preliminary stages are needed.

Tai Chi and Fall Risk

Tai chi practice in the older and at-risk population reduces the risk of falls (with the most robust results in the short-term) and may reduce the risk of injury from falls; no effect is seen when measuring time to the first fall.

Secnidazole Oral Granules (Solosec)

The FDA has approved the first oral single-dose treatment for bacterial vaginosis in adult women.

Etiology of Acute Liver Failure and Next-generation Sequencing

Metagenomic next-generation sequencing was applied to examine serum from 204 adult patients with acute liver failure (ALF). Researchers identified a potential viral etiology in eight of the 187 patients with ALF of indeterminate etiology. Potential pathogens identified in these included HSV-1, HBV, parvovirus B19, CMV, and HHV-7.

Do Antibiotics Reduce Hormonal Contraceptive Effectiveness?

This is a systematic review of studies evaluating the effect of concomitant non-rifamycin antibiotics use on hormonal contraceptive effectiveness. Although data are limited, there is no evidence to support the existence of drug interactions.