Internal Medicine
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Is It Safe to Stop Digoxin for Heart Failure?
In a large older patient heart failure with reduced ejection fraction hospitalizations database, the outcome of withdrawing digoxin vs. continuing digoxin was examined at 30 days and up to four years of follow-up. Withdrawing preadmission digoxin in hospital resulted in higher mortality at 30 days and more readmissions at six months, one year, and four years.
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Complete Revascularization After STEMI: Do We Finally Know the Answer?
In this largest trial to date, patients who were randomized to complete revascularization by percutaneous coronary intervention (PCI) following successful intervention at the time of ST-elevation myocardial infarction (STEMI) had a lower risk of cardiovascular death, myocardial infarction, and ischemia-driven revascularization vs. patients who underwent culprit lesion-only PCI.
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Are the Changes New, Recent, or Old?
Imagine examining the ECG in the figure below without any accompanying clinical information. How would one interpret this tracing? What might one suspect is going on?
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Imipenem, Cilastatin, and Relebactam Injection (Recarbrio)
The FDA has approved a new antibacterial drug combination for complicated urinary tract infections and complicated intra-abdominal infections.
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Hot Beverages and Esophageal Cancer
In a cohort of more than 50,000 people, there was a higher risk of esophageal squamous cell carcinoma in those who consumed higher quantities of mostly black tea at hotter temperatures.
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Reducing Mortality in Stable Ischemic Heart Disease Patients
A multivariate analysis of a large registry of patients with stable ischemic heart disease revealed that beta-blocker use was associated with lower mortality only when prescribed in the first year after acute myocardial infarction.
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Atorvastatin: What Is Good for the Heart Is Good for the Kidneys
For patients at risk of or who already have been diagnosed with cardiovascular disease and are taking atorvastatin, an added benefit is improved kidney function in a dose-dependent manner.
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Poor Diet May Cause More Than 80,000 Cancers Each Year in the United States
In a recent analysis, investigators noted a correlation between a diet loaded with processed red meat and various types of cancers.
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Plasma Omega-3 Polyunsaturated Fatty Acids and Healthy Aging
In a cohort of 2,622 adults, higher levels of plasma long-chain omega-3 polyunsaturated fatty acids were associated with a lower risk of unhealthy aging.
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Omega-3 Fatty Acids vs. Olive Oil to Prevent Vascular Events
In a cohort of 15,480 adults with diabetes, there was no significant difference in the risk of serious vascular events when comparing supplementation with 1 g of omega-3 fatty acid vs. an olive oil placebo.