Internal Medicine
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Neuropathy After Total Knee Arthroplasty
In a large series of cases from the Mayo Clinic, 54 cases of new neuropathy occurred in 14,450 total knee arthroplasties. Most were isolated peroneal neuropathies. No specific risk factors were identified.
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NOACs vs. Warfarin: What Are the Data in Patients With Traumatic Brain Injury and Intracranial Hemorrhage?
A three-year analysis of a prospectively maintained database with traumatic brain injury patients revealed that novel oral anticoagulant use is associated with increased risk of intracranial hemorrhage progression, neurosurgical intervention, and mortality.
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The Health Effects of Magnesium: Part 1
Magnesium, an important dietary ingredient and supplement, has both long-standing and emerging clinical evidence for efficacy in treating a variety of health conditions. To do this mineral justice, we are covering this extensive information in two parts. Part 1 will focus on basic science and physiology, general dietary recommendations, supplemental forms, laboratory testing, and dosing. Part 2 will review some of the clinical trials and research on the connection between low magnesium intake and diseases, such as diabetes, as well as the data on the use of supplemental magnesium for treatment of these diseases.
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Gingko Benefits for Tinnitus?
Twelve weeks of twice-daily Ginkgo biloba extract improved symptoms as effectively as pentoxifylline in 200 adults with chronic tinnitus.
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Mindfulness Yoga for Managing Psychological Symptoms of Parkinson’s Disease
A mindfulness yoga program was more effective than stretching and resistance training in addressing the symptoms of depression and anxiety in patients with mild to moderate Parkinson’s disease; both interventions showed equal efficacy in improving symptoms related to motor impairment. -
Intravenous Thrombolysis Prior to Mechanical Thrombectomy Improves Outcome
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Are Steroids Indicated in the Treatment of Acute Spinal Cord Injury?
In a comprehensive review of published literature and meta-analysis of clinical trials of acute spinal cord injury treatment with high-dose steroids within eight hours of onset, the authors concluded that there is no benefit regarding neurological recovery and function and an increased risk of adverse side effects from gastrointestinal bleeding.
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Adiposity Is Related to Cerebrovascular and Brain Volumetry Outcomes
In this prospective longitudinal study investigating the potential mechanistic link between adiposity and vascular cognitive impairment, anthropometric and metabolic hormone adiposity predictors were differentially associated with cerebrovascular and brain volumetry outcomes by sex in older individuals.
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Lifestyle and Environmental Risk Factors for Chronic Inflammatory Demyelinating Polyradiculoneuropathy
In a large Italian database-derived, case-control study of dietary and environmental factors, antecedent infections and diet appeared to influence the onset and course of chronic inflammatory demyelinating polyradiculoneuropathy. The diagnosis and treatment of this disorder remain a challenge.
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Effects of Probiotics on Cognition and Fall Risk in Patients With Cirrhosis
Patients with cirrhosis and mild cognitive impairment and falls were randomized to a probiotic formulation vs. placebo. Probiotic treatment improved cognitive outcomes and reduced the risk of falls.