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Endotracheal tubes (ETTs) coated with antimicrobial substances can reduce bacterial adhesion on the tube, block biofilm formation, and reduce bacterial burden in tracheal secretions. Various antimicrobial agents have been employed for this purpose.
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This clinical study was carried out to test the hypothesis that acetazolamide (Diamox®) would correct metabolic alkalosis and facilitate weaning in intubated patients with severe chronic obstructive pulmonary disease (COPD) who had elevated serum bicarbonate and were alkalemic.
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In this issue: Examining the three arms of the ACCORD trial; and FDA Actions: clopidogrel, dexlansoprazole, and tamsulosin.
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Endotracheal intubation is a procedure fraught with multiple, potentially life-threatening complications.
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Kim and associates conducted a population-based, retrospective cohort study of medical patients admitted to acute care hospitals throughout the state of Pennsylvania between July 2004 and June 2006.
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The authors conducted a single-center, randomized, non-blinded study of critically ill patients who were expected to need mechanical ventilation > 24 hours.
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FDA is reviewing safety of TZDs; SSRI use with tamoxifen; Metformin smells like fish; FDA Actions.