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Patients with neuromuscular disease who are intubated and subsequently fail multiple spontaneous breathing trials are often relegated to placement of a tracheo-stomy and continuous mechanical ventilation.
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In this issue: New reports about proton pump inhibitors and the effects of gastric suppression, pioglitazone vs vitamin E for non-alcoholic steatohepatitis, metformin and vitamin B12 deficiency, and FDA Actions.
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Peterson and colleagues at rush university medical Center carried out an observational study of ICU patients' oral nutritional intake in the 7 days following extubation after mechanical ventilation for acute respiratory failure.
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This study sought to determine whether the coagulo-pathy associated with chronic liver disease specifically the elevated International Normalized Ratio (INR) frequently present in patients with advanced disease is protective against venous thromboembolism (VTE) in hospitalized patients.
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Difficult intubations are usually the result of a difficult airway, sometimes anticipated and sometimes not.
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The value of restoring and maintaining sinus rhythm in patients with atrial fibrillation remains controversial.
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The ACC/AHA guidelines give a class ii b recommendation for surgery in asymptomatic patients if aortic stenosis is very severe (area < 0.6 cm2) and operation risk is low. However, the outcome of this approach vs. following patients until symptoms or left ventricular dysfunction occurs has not been tested.
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Atrial septal defects (ASD) are among the most common congenital heart defect found in the adult population. Although they are often diagnosed and treated in childhood or infancy, some patients survive into adulthood with unrepaired ASDs.
