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Atherosclerotic plaques in the aortic arch are considered to be a potential source of embolism to the brain and a cause of some ischemic strokes, but the role of complex plaques (> 4 mm thickness, ulcerated, superimposed thrombi) in the proximal descending aorta (DAo) is uncertain.
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New reports about proton pump inhibitors and the effects of gastric suppression, pioglitazone vs vitamin E for non-alcoholic steatohepatitis, metformin and vitamin B12 deficiency, and FDA Actions.
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Peripheral and central nervous system involvement is common in Sjögren's syndrome, and may mimic multiple sclerosis or neuromyelitis optica.
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Nine of nineteen patients with monoclonal gammopathy, referred for evaluation of peripheral neuropathy, were found to have one or more clinical signs of CNS involvement.
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In this large, well-powered, prospective, randomized trial, treatment of Alzheimer's patients with a high-dose statin did not have a significant effect on cognitive decline.
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Deep brain stimulation (DBS) is an effective treatment in Parkinson's disease with motor fluctuations and dyskinesias. However, given the potential adverse events, proper patient selection is vital.
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Increased intake of chocolate was associated with higher rates of depression on a mood screening instrument in this cross-sectional study. Whether cause and effect or self-treatment, the generally accepted idea that chocolate is comfort food appears in doubt.
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