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Mediterranean Diet Pairs Well with Immune Checkpoint Blockade

The popular healthy diet boosted response to unique cancer therapy among patients with advanced melanoma.

How Vitamin Intake Affects Migraine Prevalence

In a large population-based survey, 21.6% of participants reported having severe headaches or migraine. Those reporting severe headaches also reported a lower intake of thiamine and riboflavin, based on 24-hour recall of food intake. There also was an inverse relationship between thiamine intake and reports of severe headaches.

Vitamin D3, Omega-3, and Their Effects on Frailty in Older Patients

Data from a large, randomized trial that included 25,871 adults age 50 years or older indicated 2,000 daily units of vitamin D3 and 1 g daily of omega-3 fatty acid supplementation did not affect frailty.

Multivitamin-Mineral Supplementation vs. Cocoa Extract for Cognition

This large, randomized trial followed participants for three years and determined that daily use of a cocoa supplement was not associated with cognitive enhancement in older adults, whereas a multivitamin supplement was associated with significant cognitive benefits.

Cutting Total Calorie Intake Is More Effective for Weight Loss

Researchers found monitoring total caloric intake may be more effective for losing weight than intermittent fasting.

Do Spinal Cord Stimulators Really Help for Chronic Pain?

The results of a comprehensive analysis of a large clinical database regarding treatment of patients with chronic low back pain did not support the benefit of spinal cord stimulators compared to conventional medical management for chronic pain.

An Easy Measure of Potentially Harmful Salt Intake

Those who rarely or never added salt to their food and strongly adhered to the Dietary Approaches to Stop Hypertension diet exhibited the lowest incidence of subsequent cardiovascular disease.

Effectiveness of Dietary Supplements on Lipid and Inflammatory Biomarkers

In a comparison of rosuvastatin 5 mg/day, six common dietary supplements marketed for improving heart health, and placebo, none reduced high-sensitivity C-reactive protein levels. Only rosuvastatin significantly reduced LDL cholesterol levels compared to placebo.

For Older Americans, More Steps Lead to Better Cardiovascular Health

In a meta-analysis, researchers found walking 6,000 to 9,000 steps daily lowered the risk of cardiovascular disease by 40% to 50% vs. walking 2,000 steps daily.

Considering Periodontal Disease as a Risk Factor of Cardiovascular Disease

Researchers used data from the 2013 to 2014 period of the National Health and Nutrition Examination Survey to study possible connections between poor oral health and the likelihood of developing cardiovascular disease.