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Respiratory Syncytial Virus — Not Just a Disease of Children

Respiratory syncytial virus is a significant cause of morbidity and mortality in the elderly.

A Novel Rifabutin-Containing Combination Regimen Is Effective for Eradicating H. pylori Infection

A Phase III, randomized, controlled trial found a significantly higher eradication rate for H. pylori with a 14-day regimen of rifabutin, amoxicillin, and omeprazole compared to 14 days of amoxicillin and omeprazole.

Respiratory Syncytial Virus — Effective Prevention Still Needed

Prevention of respiratory syncytial virus infection is needed but challenging. New studies show some favorable effectiveness on infant outcomes with both vaccination of healthy pregnant women and passive single-dose immunization of prematurely born babies.

Repeat Infections with Endemic Coronaviruses and Possible Implications for COVID-19

Repeat infection with endemic seasonal coronavirus occurs commonly and raises concerns about immunity to SARS-CoV-2 as well as about the efficacy of vaccines in the protection against infection due to this virus.

Dexamethasone for COVID-19 Inpatients Requiring Oxygen

Dexamethasone administration is associated with reduced 28-day mortality in oxygen-requiring COVID-19 patients, including those receiving mechanical ventilation.

The COVID-19 Pandemic: What Comes Next? Lessons from Seasonal Coronaviruses

In temperate regions other than China, human seasonal coronaviruses circulate most heavily during the winter months, overlapping with influenza and respiratory syncytial virus — and this may be the eventual pattern for SARS-CoV-2.

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Metronidazole Neurotoxicity Is Real; 2020 Updated LTBI Treatment Guidelines; Risks of Hookah Smoking

A New Treatment for Recurrent Bacterial Vaginosis?

In this randomized controlled trial of 228 women, Lactobacillus crispatus CTV-05 (Lactin-V) applied vaginally for 11 weeks reduced the incidence of recurrent bacterial vaginosis from 45% in the placebo arm to 30% in the Lactin-V arm.

Rotavirus Vaccine Is Safe and Effective

Routine rotavirus vaccination of infants, when implemented broadly, is safe and is associated with reductions in diarrhea-related hospitalizations, mortality, and morbidity (such as malnutrition) in children.