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The CDC has published a new set of recommendations aimed at preventing health care-associated infections by optimizing hand hygiene in health care personnel. The following is a summary of some of those recommendations, selected because of their strength and/or novelty.
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Passage through the human gastrointestinal tract enhances the infectiousness of Vibrio cholerae.
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In this feature, brief items, primarily gleaned from abstracts or articles in journals and other resources not commonly perused by most US
infectious disease physicians, will be presented, usually without comment.
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High-Dose Rofecoxib Confirmed Prothrombotic, Study Shows; Losartan Better Than Atenolol for LVH Treatment; Lisinopril, Not Losartan, Improves Myocardial Perfusion; New Fluoroquinolone Study; Warfarin After MI Better Than Aspirin Alone; FDA News
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Once a final decision is made regarding some proposed research involving very young children and an older smallpox vaccine, there could be long-term repercussions for IRBs nationwide.
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The 10-page human subjects consent form proposed for the Dryvax vaccination study of children, ages 2 to 5, has a number of flaws, according to the IRBs and experts who have reviewed the study proposal and consent form.
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The proposal for the study, A Multicenter, Randomized Dose Response Study of the Safety, Clinical and Immune Responses of DryVax Vaccine Administered to Children 2 to 5 Years of Age, provides the following details.
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Although Japanese encephalitis rarely occurs in travelers, certain groups and subsets of individuals have a risk of infection that can reach 1 in 5000 travelers per week. It is crucial to recognize those with increased risk, and to seriously consider immunizing them in order to prevent the potentially devastating sequelae of Japanese encephalitis.
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Careful evaluation of epidemiologic data from recent African outbreaks of meningococcal disease suggests that significant risks now extend beyond the sub-Saharan belt through the Rift Valley and Great Lakes regions into Mozambique, then into Namibia and Angola.
