Infectious Disease Alert
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Playing Opossum: A New Model of Antibiotic and Immune Resistance
Researchers observed nongrowing cells of Salmonella that remained persistent, resisted antibiotics, and retained infectivity.
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Rifamycin Delayed-Release Tablets (Aemcolo)
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A Rabies Death in Virginia
A Virginia resident who had not received pre- or post-exposure prophylaxis died of rabies resulting from a dog bite during a prolonged trip to India. Many exposed healthcare workers subsequently received post-exposure prophylaxis.
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Rotavirus Vaccine and Hospitalization for Seizures
In an analysis of insurance claims for 1.8 million U.S. children with 2,950 recorded seizures, researchers found that the risk of hospitalization for seizures was 24% lower in rotavirus-vaccinated children.
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Duration of Intravenous Antibiotic Therapy for Late-Onset Neonatal Group B Streptococcal Bacteremia
Although standard treatment of late-onset neonatal group B Streptococcus bacteremia includes intravenous antibiotic therapy for 10 days, shorter courses seem safe and effective.
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A Nosocomial Outbreak at the NIH Clinical Center From Sphingomonas koreensis, a Rare Human Pathogen
A genomic and epidemiologic investigation of an outbreak at the National Institutes of Health Clinical Center determined that S. koreensis was an opportunistic human pathogen that persisted in a reservoir in the hospital plumbing.
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Treatment of Gram-Negative Bacteremia: How Long Is Long Enough?
Antibiotic administration for seven days is sufficient in stable patients with Gram-negative bacteremia.
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Infectious Disease Alert Updates
Circulation of a Novel Vaccinia Virus in Brazilian Equids; Chopin’s Brandied Heart; The Scent of Malaria
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Antibiotic Decision-Making Between Medical and Surgical Teams
In an observational study conducted at an academic medical center in London, researchers looked at factors involved in decision-making. The presumptive diagnosis of infection by the emergency department (ED) influenced decision-making by both medical and surgical admitting teams. Medical teams tended to use a multidisciplinary approach to antibiotic decision-making. Surgical teams often delegated antibiotic decision-making to the most junior members of the surgical team.
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Acute Flaccid Myelitis 2018
The number of reported cases of acute flaccid myelitis, a paralytic disease of unknown etiology, has increased.