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Genetically engineered B lymphocytes were used for rapid detection and identification of pathogens, a methodology with potential use in diagnostics, biowarfare defense, and biomonitoring of food and water.
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Compliance with a protocol for managing catheter-related bacteremia was improved from 56% to 75% simply by sending a reminder by e-mail.
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An outbreak of Pseudomonas surgical-site infections was traced to the infected thumbnail of a cardiac surgeon. The outbreak stopped after the infected nail was removed.
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The FDA has approved Pfizer's eplerenone (Inspra) for the treatment of congestive heart failure (CHF) in patients who have sustained a myocardial infarction. The drug is a selective aldosterone blocker, a new class of drug for the treatment of CHF.
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The results of genetic analysis of a strain of S aureus with high-level resistance to vancomycin suggest that this resistance was the consequence of genetic transfer from a VRE to an MRSA, each present in and on the unfortunate patient who served as the incubator.
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In a multicenter study of occupational HIV exposures, 38% of source patients had genotype mutations associated with resistance to antiretroviral drugs. Recent antiretroviral treatment history was highly associated with resistance.
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The following summary of selected abstracts from 3 meetings will be published in multiple parts. The 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) met in Chicago September 14-17, 2003.
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The evolution of antibiotic resistance in Staphylococcus aureus is an epic saga. Resistance to penicillin was first reported in the 1940s, at a time when the drug still remained in short supply.
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An outbreak of tetanus involving 6 (and possibly 7) injection drug users in England and Wales has officials concerned that others may be at risk. Six of the cases occurred during the past 3 weeks and were spread throughout the country, suggesting contamination of some type of drugpossibly heroin.
