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Evidence-based updates in primary care medicine By Louis Kuritzky, MD
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The notification of the CDC of 2 laboratory-confirmed cases of cyclospora infections on June 28, 2013 was their first evidence of an outbreak.
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Clinically relevant doses of bactericidal antibiotics (quinolones, aminoglycosides and β-lactams) were shown to cause mitochondrial dysfunction and overproduction of reactive oxygen species in mammalian cells in vitro and in mice, leading to oxidative tissue damage.
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The risk of cardiovascular mortality with current use of the azalide (but not with past or future use) was increased (rate ratio, 2.85; 95% CI 1.13 to 7.24).
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NSAIDs and cardiovascular risk; new antithrombotic guidelines; warfarin during surgery; Pfizer selling Viagra online; azithromycin and cardiovascular risk; and FDA actions.
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In a matched, retrospective cohort study, early use of daptomycin compared to vancomycin in MRSA bacteremia with vancomycin MICs > 1 ìg/mL resulted in improved clinical outcomes, including less clinical failure at 30 days, lower mortality and less persistent bacteremia.
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Two recent studies from the Centers for Disease Control and Prevention evaluated the risks for spread of respiratory viruses from travelers on commercial airplanes.
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The novel coronavirus which emerged in the Middle East, now officially called MERS-CoV (Middle East respiratory syndrome coronavirus), has continued to cause new, often fatal infections. As of June 7, 2013, there have been 55 laboratory-confirmed cases of infection worldwide, according to the Centers for Disease Control and Prevention.
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Snooping out counterfeit anti-malarials; Teflon to some; Rethinking TB screening in a low risk population
