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Acetaminophen (known as paracetamol outside the United States) is the most commonly used analgesic in the world, usually considered to be safe and benign.
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Clinicians who send samples to the 95% of U.S. laboratories that test for Clostridium difficile infection using an enzyme-immunoassay (EIA) for toxins A and B are often frustrated by a negative laboratory result that doesn't fit their clinical impression or their olfactory suspicions.
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Central line-associated infections, particularly bloodstream infections (BSI), remain a huge issue in our technological age.
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Outpatients with uncomplicated seasonal influenza were treated with single doses of IV peramivir 300 mg/kg, 600 mg/kg, or placebo. Peramivir significantly reduced the time to alleviation of symptoms at both doses compared with placebo. Peramivir was well-tolerated, and side effects were comparable to placebo.
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Using a quality improvement (QI) process, ICU delirium, physical rehabilitation, and functional mobility were significantly improved and associated with a decreased length of stay.
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The Centers for Disease Control and Prevention guidelines to prevent infection with carbapenem-resistant pathogens include the following recommendations.
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Robert Rapp, PharmD, professor of pharmacy at the University of Kentucky Chandler Medical Center, is an outspoken advocate for antibiotic stewardship to preserve the efficacy of our remaining antibiotics against rising drug resistance.
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The continuing global emergence of multidrug resistant gram negative pathogens bugs that are virtually impervious to all antibiotics and can transfer resistance mechanisms between species means infection prevention is more critical than ever during every patient encounter.
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Threatening to spread to North America after originating in hospitals in India, the pan-resistant New Delhi metallo-beta-lactamase (NDM-1) enzyme has been linked to a fatal infection in Canada.
