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Nasally Administered Flu Vaccine Comes to United States; Paxil: Not
Recommended for Children; Prilosec Granted OTC Status; Finasteride and
Prostate Cancer; Xolair: First Biologic Agent for Asthma; West Nile
Virus Update; Study Shows COX-2 Inhibitors Appear Safe with Aspirin in
Asthma Patients; Lamictal Approved for Bipolar Disorder
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There has been some controversy on the role of taxanes in combination with platinum for the treatment of ovarian cancer. In the current report, patients who relapsed after a disease-free interval of 6 months or more were randomized in 2 large, multicenter trials conducted in Europe to receive either platinum (or typical platinum-based regimens) or paclitaxel plus platinum.
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Women who survive breast cancer may be at a lower risk of developing coronary artery disease compared with women without a history of breast cancer.
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The development of an isolated supraclavicular node recurrence of breast cancer after primary surgical resection (including axillary node dissection) was found, upon review of the tumor registries of 8 community hospitals in The Netherlands, to occur very uncommonly (less than 1%). Examination of clinical outcomes for these patients indicates that isolated supraclavicular recurrence is an antecedent of disseminated disease, in that, even with local control (as achieved by radiation therapy), the great majority of patients soon develop systemic disease.
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Since the introduction of the 3-weekly CHOP (cyclophosphamide, adriamycin, vincristine, prednisone) chemotherapy 25 years ago, many efforts have been undertaken to improve the efficacy of multicycle polychemotherapy for patients with aggressive lymphoma.
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Following radiation therapy, adjuvant extrafascial hysterectomy decreased the risk of relapse for patients with bulky stage IB cervical cancer without improving survival.
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The FDA has approved the first nasally administered flu vaccine to be marketed in this country. Medimmunes FluMist is also the first influenza vaccine to use live virus.
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News from the KEEPS Study: HRT Does Not Decrease Progression of Atherosclerosis Over 4 Years of Treatment
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In this prospective cohort study of 161 nulligravid women, there was no reliable threshold of uterine length or flexion angle measurements that were predictive of painful or difficult insertions. History of severe dysmenorrhea was the only predictor of insertion pain.
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Barriers to guideline-adherent care for advanced ovarian cancer are impacted by geographic proximity to a high-volume hospital and travel distance. However, these geographic barriers disproportionately affect racial minorities and women of lower socioeconomic status.
