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Although the levonorgestrel intrauterine system (LNG IUS) has been shown to be an effective treatment for heavy menstrual bleeding (HMB), previous clinical trials included rigorous criteria focused primarily on measuring the severity of bleeding.
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During the past few months, there has been a pleth-ora of articles published with important clinical implications, and I have found it difficult to pick just one to review.
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LAP2 was a phase 3 clinical trial to assess the non-inferiority of laparoscopy compared with laparotomy for recurrence of uterine cancer after surgical staging.
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This Phase 1 clinical trial evaluated the safety and pharmacokinetics of intraventricular immune-chemotherapy with twice weekly rituximab (10 mg and 25 mg) and methotrexate in 14 patients with recurrent central nervous system lymphoma (primary or secondary).
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Aspirin use and AMD risk; using NSAIDs and antihypertensive agents; and FDA actions.
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In a randomized, Phase 2 trial, weekly maintenance cetuximab for 12 weeks after concomitant definitive radiation therapy/cetuximab induction was associated with better disease-free survival at 1 year.
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In an observational study conducted in Germany of more than 600 anemic cancer patients receiving parenteral iron (ferric carboxymaltose), hemoglobin levels were shown to rise significantly.
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Statin use among cancer patients with diverse malignancies is associated with reduced cancer-related mortality.
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A 52-year-old female presented with right flank pain, elevated bilirubin, and mild jaundice to her primary care physician. Endoscopic retrograde cholangiopancreatography demonstrated a common bile duct stricture just above the pancreatic head with a suggestion of neoplasia.
