Hematology/Oncology
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Antibiotics for Intra-abdominal Infections: Less Is More
Complicated intra-abdominal infections cause significant morbidity and mortality, especially in the elderly. Often these infections are treated with antibiotics until all the signs and symptoms of the systemic inflammatory response syndrome resolve, typically for 7 to 14 days.
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Duration of Antibiotic Treatment for Vertebral Osteomyelitis
Three hundred fifty-nine patients with pyogenic vertebral osteomyelitis were randomized to 6 weeks vs. 12 weeks of antibiotic treatment in an open-label controlled trial. Six weeks of antibiotics was found to be not inferior to 12 weeks of treatment.
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VTE Occurs Frequently in Patients with Sepsis
The purpose of this multicenter study was to prospectively determine the incidence of VTE among ICU patients with sepsis and septic shock, and to identify independent risk factors for VTE in these patients.
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Inferior Vena Cava Filters and Recurrent Pulmonary Embolism
Placement of retrievable inferior vena cava filters in individuals with concurrent DVT does not reduce the risk of recurrent pulmonary embolism.
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Risk of NSAID use in patients receiving antithrombotic therapy after myocardial infarction
Among patients receiving antithrombotic therapy after MI, the use of NSAIDs was associated with increased risk of bleeding and excess thrombotic events, even after short-term treatment.
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Early, goal-directed therapy of septic shock
One thousand two hundred sixty patients with early septic shock were randomized to early, goal-directed therapy vs. usual care. Hemodynamic management according to a strict protocol did not lead to an improvement in outcome.
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Hospital wards with higher rates of antibiotic prescribing associated with increased risk for C. diff infection
A retrospective observational study found that among hospitalized patients, ward-level antibiotic prescribing was associated with a significantly increased risk for C. difficile infection beyond what would be expected with patient-level antibiotic use.
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Vasospastic angina with myocardial infarction – more dangerous than once thought?
Patients with vasospastic angina and a type II myocardial infarction have a worse prognosis than previous believed.
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Do I need atypical coverage for all non-ICU hospitalized patients with community-acquired pneumonia?
Is the accepted treatment for CAP enough, or could we do more?
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Chemotherapy in Latinas: Stress Management Needs and Techniques
Healthcare providers and women with recent chemotherapy for breast cancer commented on some of the stress management challenges as well as techniques that are already being used to address them.