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  • Obesity—Overrated As A Coronary Risk Factor?

    Overweight is associated with no excess mortality, particularly in the older age groups.
  • Pharmacology Watch: Is Nesiritide Associated with a Higher Death Rate?

    Nesiritide, Scios' intravenous recombinant form of human B-type naturetic peptide, has been widely used for the treatment of congestive heart failure in hospitalized patients.
  • Lush Desert in Arizona — A Sign of Trouble Ahead?

    The exuberant rainfall in the southwestern United States this year has led to the greening of the deserts, highlighted by spectacular displays of wildflowers. But it may not be just the plant life that has benefited. A number of human pathogens may find the conditions just right.
  • CDC Releases New Recommendations for Meningococcal Vaccine

    On February 10, 2005, the CDCs Advisory Committee on Immunization Practices recommended routine meningococcal immunization of all children between ages 11 and 12, with catch up immunization targeted to teens entering high school and college freshmen living in dormitories.
  • TB, BCG, PPD, and Travelers

    The interpretation of tuberculin skin tests (tst) is challenging and controversial, especially in the face of previously administered BCG vaccine. In Switzerland, a country where TB infection is not common but where BCG had previously been routinely given, Zysset and colleagues prospectively evaluated 2- step (second test done 8-15 days after the first for possible booster effect) TST results in 5117 hospital employees, in view of potential risk factors for TB infection.
  • Clinical Briefs in Primary Care supplement

  • Infection and Anemia

    Anemia of Chronic Disease (ACD) is a common disorder occurring in patients with acute and chronic inflammatory conditions. ACD is associated with infectious diseases, as well as with malignancies and autoimmune disorders. The pathophysiology of ACD involves abnormalities in iron homeostasis, impaired erythropoiesis, and blunted responses to erythropoietin, brought about by mediators of inflammation such as TNF-alpha, interferon-gamma, and interleukins.
  • Marburg Virus Infection

    In 1967, in marburg, a medieval university town north of Frankfurt, Germany, on the Lahn River, several employees of a Behringwerke AG, a manufacturer of vaccines, were hospitalized at the University Medical Clinic with a severe influenza-like illness.
  • Efficacy of Oral Cholera Vaccine

    This article evaluates a mass immunization program with recombinant cholera-toxin B subunit, killed whole cell (rBS-WC) cholera vaccine in Beira, Mozambique, a city where seroprevalence of HIV infection is 20-30%.
  • Updates By Carol A. Kemper

    In vitro resistance to daptomycin associated with clinical failure during treatment for MRSA infection has not been well documented. In vitro resistance to daptomycin is uncommon, de novo-resistant clinical isolates have not yet been reported, and the incidence of resistance, occurring during treatment is believed to be very low. The mechanism of resistance is not even known.