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Kahlenborn and colleagues performed a meta-analysis of case-control studies published after 1979 that focused on the use of oral contraceptives and the risk of premenopausal breast cancer.
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The resection of tumor nodules (or cytoreduction) before primary chemotherapy has been linked closely with survival in patients with advanced epithelial ovarian cancer. Chi and colleagues set out to evaluate the merits of cytoreduction completeness in a homogeneous cohort of ovarian cancer patients with bulky metastatic disease.
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The lead paper in the November issue of Obstetrics and Gynecology should stimulate lively discussion regarding the counseling of patients of advanced maternal age (AMA), and, if taken at face value, could impact the field of prenatal diagnosis, in general.
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Clostridium difficile diarrhea and colitis have now emerged as common nosocomial infections in hospitals throughout the developed world. Alarmingly, recent epidemiological studies in ambulatory settings have documented C. difficile infection in both adults and children who lack the usual risk factors of prior antibiotic use or hospitalization.
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Given its lack of benefit, possible harms, and expense, magnesium sulfate should not be used for tocolysis.
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RFA should be considered a first-line therapy even after the first episode of symptomatic AFL. There is a better long-term success rate, the same risk of subsequent AF, and fewer secondary effects.
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Among adults diagnosed with heart failure who had no prior statin use, incident statin use was independently associated with lower risks of death and hospitalization among patients with or without coronary heart disease.
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A meta-analysis of 10 studies of heparin used either for prophylaxis or for treatment suggests that venous thromboembolism related to heparin-induced thrombocytopenia occurs frequently in patients previously treated with unfractionated heparin, but uncommonly in those on low molecular weight heparin.
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The stroke and death rates at one and 6 months were lower in patients with symptomatic carotid stenosis (> 60%) treated with endarterectomy versus stenting.