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Anemia of Chronic Disease (ACD) is a common disorder occurring in patients with acute and chronic inflammatory conditions. ACD is associated with infectious diseases, as well as with malignancies and autoimmune disorders. The pathophysiology of ACD involves abnormalities in iron homeostasis, impaired erythropoiesis, and blunted responses to erythropoietin, brought about by mediators of inflammation such as TNF-alpha, interferon-gamma, and interleukins.
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In 1967, in marburg, a medieval university town north of Frankfurt, Germany, on the Lahn River, several employees of a Behringwerke AG, a manufacturer of vaccines, were hospitalized at the University Medical Clinic with a severe influenza-like illness.
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This article evaluates a mass immunization program with recombinant cholera-toxin B subunit, killed whole cell (rBS-WC) cholera vaccine in Beira, Mozambique, a city where seroprevalence of HIV infection is 20-30%.
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In vitro resistance to daptomycin associated with clinical failure during treatment for MRSA infection has not been well documented. In vitro resistance to daptomycin is uncommon, de novo-resistant clinical isolates have not yet been reported, and the incidence of resistance, occurring during treatment is believed to be very low. The mechanism of resistance is not even known.
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Is Holding NSAIDs Prior to Surgery Rational?; Low-Dose Aspirin: Men vs Women; FDA Actions
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Insomnia is associated with an increased risk of falls in nursing home residents. The use of hypnotics is not.
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The management of neuropathic pain (NPP) presents a challenge to clinicians of all specialties, since disorders associated with NPP span the gamut of medical disciplines.
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The 12-lead ECG in the Figure was obtained from a 69-year-old woman with a history of a previous large myocardial infarction. She was aware of an extra beating of her heart, but was otherwise asymptomatic at the time this tracing was recorded. How would you interpret this tracing in view of this presentation, her prior history, and the knowledge that the patient was known to have complete right bundle branch block on prior ECG?
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In patients with vascular disease or diabetes mellitus, long-term vitamin E supplementation does not prevent cancer or major cardiovascular events and may increase the risk for heart failure.
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Screening for bipolar disorder in primary care settings can aid in its diagnosis.
