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There appears to be an increase in ovarian cancer with long-term estrogen-only hormone replacement therapy.
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Ambulatory blood pressure monitoring is a useful adjunct for evaluating white coat hypertension, but little is known about its effect on BP. Thus, Hermida and associates from Spain studied 538 patients with mild-to-moderate office hypertension using ABPM for 48 hours.
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There is evidence that diet could play a role in Alzheimer's disease (AD) risk. This epidemiologic study examined the risk of AD between quartiles of calorie, carbohydrate, fat, and protein intake after adjusting for confounders.
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Sleep disorders are extremely common and the primary care physician (PCP) can play an important role in their identification and management. The PCP is the first line of defense for identifying patients with sleep disorders and initiating appropriate evaluation and managing long-term treatment.
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In patients with heart failure and diabetes, metformin is not associated with harm and may reduce all cause mortality.
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The FDA has approved a new drug for the treatment of advanced breast cancer.
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Asymptomatic brain MRI findings of infarct, cerebral aneurysms and benign tumors were fairly common in the general population. The clinical significance of these findings is unknown.
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Two hundred eighty-eight patients hospitalized with severe community-acquired pneumonia (CAP) were followed for 28 days in a prospective multicenter study. At day 7, 25% of patients had resolution of CXR abnormalities and 56% had improvement. At day 28, 53% of patients had resolution of CXR abnormalities and 78% had clinical cure. By multivariate analysis, delayed resolution of CXR abnormalities by day 7 was associated with multilobar disease, dullness to percussion by physical exam, elevated CRP (> 200 mg/L), and tachypnea (respiratory rate > 25/min.) on admission.
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A randomized controlled trial in Australia showed that a 16 week program of tai chi reduced falls by 33% in a group of elderly persons.
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Can Exenatide be Substituted for Insulin?, Treatment of Osteoporosis Saves Bones AND Lives, and MRSA in These United States
