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A randomized, double-blind, placebo-controlled trial conducted in England among 687 children 10-60 months of age with acute virus-associated wheezing compared a five-day course of oral prednisolone (10 m once a day for children 10-24 months of age and 20 mg once a day for older children) with placebo.
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For this study, 12,765 patients from the large French Hospital Database for HIV with CD4+ lymphocyte counts < 200 cells/uL who received cART during 2000-2005 were selected.
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Influenza activity has been relatively low thus far in the 2008-2009 season in the United States. However, of the influenza viruses isolated and tested to date, there is significant resistance among the influenza A (H1N1) viruses to the antiviral oseltamivir.
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In this issue: FDA warning on topical anesthetics; antipsychotics increase sudden cardiac death; the step up vs step down debate; treating pain, fatigue, mood, and sleep in fibromyalgia; FDA Actions.
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Placenta accreta can represent a real clinical conundrum, especially if it is unrecognized before delivery.
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A few studies have suggested that we tend to underestimate blood loss during deliveries and cesarean sections. A group from Louisiana State University has addressed this issue again in a very clever way.
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Curtis and colleagues from the University of Alabama at Birmingham measured the rate of hip fracture among women who discontinued bisphosphonate therapy compared with women who remained on treatment.
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The Women's Iinternational Study of Long Duration Oestrogen after the Menopause (WISDOM) trial was a randomized, controlled trial in the United Kingdom, Australia, and New Zealand, of 3721 women aged 50-69 treated with either combined 0.625 mg conjugated estrogens and 2.5/5.0 mg medroxyprogesterone, or placebo. The original plan was to randomize 22,300 women to the study that would last 10 years.
