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Clopidogrel and proton pump inhibitors; adverse events with tamsulosin after cataract surgery; new guidelines for persistent pain in the elderly; and FDA Actions.
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This large multicenter, randomized, controlled parallel-group trial found that intensive glucose management, compared to conventional (target glucose 81-108 mg/dL vs. ≤ 180 mg/dL), increases 90-day mortality in both medical and surgical ICU patients.
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Patients presenting to the emergency department (ED) with acute chest pain are a significant portion of our health care budget.
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Observational studies have suggested statins may not only reduce arterial cardiovascular events but also venous thromboembolism.
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In a randomized, multicenter trial, chlorhexidine-impregnated sponges used in the dressing of intravascular catheters reduced catheter-related infections by 60%. Increasing the interval of catheter-related dressing changes from 3 to 7 days did not increase the rate of infection.
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Syncope is commonly accepted to be a danger sign in patients with hypertrophic cardiomyopathy (HCM). In this paper, Spirito et al report data from a registry of 1,511 patients with HCM who have been followed longitudinally at four institutions.
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Resistance to antibiotics continues to pose a serious problem in treating infections. While new pharmaceutical agents are being developed, interest in alternative treatments is also growing. Grapefruit seed extract is one commercially available antimicrobial that has attracted considerable attention.
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Several large observational studies have suggested that vitamin E supplementation lowers the risk of coronary heart disease. However, the results of large randomized controlled trials failed to show a clear benefit of a-tocopherol supplementation on cardiovascular outcomes.
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Subgroups of U.S. adults who are minorities, poor, or undereducated with chronic cardiovascular risk factors such as hypertension, diabetes, and hypercholesterolemia have large disparities in treatment for these conditions compared with white, high school-educated adults when they are uninsured or underinsured.
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According to results of a gallup organization survey released during the American College of Obstetricians and Gynecologists (ACOG) 57th Annual Clinical meeting in Chicago, women are delaying important preventive care—in the form of pregnancy and annual check-ups—as a result of the economy.
