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The oral absorption and clearance of either amoxicillin or cefaclor was tested in women who also ingested cranberry juice cocktail. Although there was modest slowing of absorption (amoxicillin and cefaclor) and decreased maximum serum drug concentration (cefaclor) when the cranberry groups were compared to control groups (water), the overall clinical effect seemed to be negligible.
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There is no agreed upon standard therapy for men experiencing inflammatory chronic prostatitis/ chronic pelvic pain syndrome (CP/CPPS). The results of this strong clinical trial suggest that a 12-week course of therapy with a specific pollen extract is significantly more effective than placebo in reducing the symptoms of CP/CPPS, especially pain.
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Concerns about the potential increased risk of prostate cancer associated with high intakes of alpha-linolenic acid (ALA; 18:3n-3) were re-assessed by the authors of this systematic review, but the aforementioned concerns could not be completely allayed.
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PPIs and Clopidogrel: Do We Have to Worry?; Surgery vs Medical Treatment for CTS; Influenza Vaccine: Flu Shot vs Nasal Mist; Beleaguered Primary Care Clinicians; Beyond Diabetes Prevention; Does Metformin Affect Thyroid Function?
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Sex hormone-binding globulin (SHBG) is a protein that might seem to be most interesting to the endocrinologist, since its sole function - until very recently - has been thought to be regulation of the availability of gonadal steroids.
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Hand hygiene and facemasks used within 36 hours of patient symptom onset resulted in a small reduction of household transmission of influenza, but adherence to recommended practices was poor despite home-based education.
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One-third of adults older than age 40 has vestibular dysfunction.
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In patients with obstructive sleep apnea who are treated with CPAP, those who report persistent sleepiness are more likely to have history of depression, diabetes, and heart disease, and to have been sleepier prior to treatment.
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The ninth atypical antipsychotic agent has been approved by the FDA. Asenapine is somewhat unique in the class with different receptor binding than risperidone and olanzapine.
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The efficacy of percutaneous closure of the LAA with the WATCHMAN® left atrial closure device was found to be non-inferior to that of standard warfarin therapy for prevention of stroke, cardiovascular death, and/or systemic embolism and, therefore, the device might provide an alternative strategy to chronic warfarin therapy for stroke prophylaxis in patients with non-valvular atrial fibrillation.
