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The relationship of stroke to myocardial infarction (MI) remains controversial. Thus, Witt and colleagues from the Mayo Clinic in Rochester, MN, evaluated a community-based cohort of 2160 patients with acute MI hospitalized between 1979 and 1998 to determine the incidence of stroke after MI and its influence on survival. Ischemic and hemorrhagic strokes were included. Follow-up averaged 5.6 years (range, 0-22 years).
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In daily clinical practice, OAC was only given to a minority (30%) of AMI patients with AF, despite the fact that OAC was associated with a 29% relative and 7% absolute reduction in 1-year mortality after adjustment for confounding variables. The results emphasize the importance of OAC treatment for AF after AMI.
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Oral amiodarone prophylaxis of atrial tachyarrhythmias after cardiac surgery is effective and well tolerated.
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There is a wide variation in presentation and course of ARVD patients, which can likely be explained by the genetic heterogeneity of the disease.
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The high rates of acute vascular events outside the coronary arterial territory and the steep rise in event rates with age in all territories have implications for prevention strategies, clinical trial design, and the targeting of funds for service provision and research.
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Fenofibrate did not significantly reduce the risk of the primary outcome of coronary death or non-fatal MI. It did reduce total cardiovascular events, mainly due to fewer non-fatal myocardial infarctions and revascularizations.
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Bacterial resistance to antibiotic treatment has concerned the medical community since the introduction of the first antibiotics in the 1920s. Development of new anti-infective agents has been precipitated by increasing resistance to older agents and classes of agents. While high rates of resistant organisms have been particularly problematic in hospital intensive care units, serious resistance now is being encountered in community-acquired infections. This review will focus on the clinical aspects of antibiotic resistance in community-acquired respiratory infections, pharyngitis, skin infections, and urinary tract infections.
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There is a role for endovascular therapy, such as stenting, as reported in Stroke, in the setting of failed medical management with anticoagulants.
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The probability of in-hospital death was higher for patients with the lowest total FOUR score than for those with the lowest total GCS score.
