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Synopsis: In asymptomatic patients with preexcitation, electrophysiologic testing can stratify the risk of future symptomatic and fatal arrhythmic events.
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Synopsis: Amiodarone is superior to placebo for cardioversion of AF when measured at 24 hours after drug administration.
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Synopsis: Death due to cardiac structural complications is rare in young Marfans patients followed carefully on medical therapy, but arrhythmogenic sudden death occurs and is more common in those with LV dilatation.
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The Centers for Disease Control and Prevention published Smallpox Vaccination and Adverse ReactionsGuidance for Clinicians in the Jan. 24th edition of Morbidity and Mortality Weekly Report.
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Pravastatin given for 3 years reduced the risk of coronary disease in elderly individuals. The PROSPER study therefore extends to elderly individuals the treatment strategy currently used in middle aged people.
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The FDA has approved cyclosporine ophthalmic emulsion for the treatment of dry eyes due to keratoconjuctivitis sicca (KCS) and associated reduced tear production. Cyclosporine is an immunomodulating agent that increases tear production in patients with KCS.
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Ice Cream-Evoked Headaches Study: A Randomized Trial of Accelerated vs Cautious Ice Cream Eating Regimen; Treatment of Antidepressant-Associated Sexual Dysfunction with Sildenafil; Prophylactic Treatment of Migraine with an Angiotensin II Receptor Blocker
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Screening for lung cancer with helical CT has high costs and uncertain benefits.
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Current guidelines for NSAID use in patients at high risk for ulcer disease recommend use of NSAIDs selective for cyclo-oxygenase-2 inhibition or nonselective NSAIDs plus a proton pump inhibitor. This study compared diclofenac plus omeprazole with celecoxib in patients with previous GI hemorrhage. Neither regimen successfully prevented rebleeding, and both exhibited significant toxicities.
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Treatment with natalizumab, an antibody to a4 integrin, led to fewer inflammatory brain lesions and fewer relapses in patients with relapsing multiple sclerosis.
