Clinical
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Postpartum Contraception Care at Catholic Hospitals
A survey using a probability sample of adult, reproductive-age women in the United States revealed that most women did not expect restrictions on care at Catholic hospitals, especially for services viewed with less stigma than abortion, and did not realize that Catholic hospitals are restricted in providing contraception and female sterilization.
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What Is the Best Oral Emergency Contraceptive for Individuals with Obesity?
In this randomized controlled trial of 70 obese women, double dosing levonorgestrel emergency contraception (3 mg vs. 1.5 mg) did not prevent more follicle ruptures and, therefore, is unlikely to improve emergency contraception performance in this population.
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Prevention of Perineal Injury During the Second Stage of Labor
This randomized clinical trial in nulliparous women demonstrated that the hands-off technique reduced the risk for perineal injuries when compared to the hands-on technique during the second stage of labor.
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Cervical Cancer Screening in Women Older than 65 Years of Age
Women diagnosed with cervical cancer after age 65 years are more likely to have locally advanced or metastatic disease, and survival decreases with increasing age and stage of diagnosis.
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Novavax COVID-19 Vaccine, Adjuvanted (NVX-CoV2373)
Novavax is authorized to be administered to patients age 18 years and older for active immunization to prevent COVID-19 caused by SARS-CoV-2.
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Rivaroxaban Monotherapy for Atrial Fibrillation in Coronary Artery Disease Patients
For patients with atrial fibrillation and stable coronary artery disease, rivaroxaban monotherapy was superior to dual therapy for preventing thrombotic and bleeding events and was associated with a lower mortality rate.
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The Value of Stress Testing in Patients with Known Coronary Artery Disease
A comparison of adenosine stress single-photon emission CT, PET, and MRI in stable patients with known coronary artery disease (CAD) showed PET to be more sensitive for detecting invasive fractional flow reserve-identified ischemic lesions. However, the sensitivity was disappointing. Patients with known CAD and new symptoms should be referred directly to invasive coronary angiography.
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Inflammatory Foods Could Accelerate Brain Aging
In the Framingham Offspring cohort of subjects, those with a higher index of inflammatory foods recorded smaller brain volume, less grey matter.
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COVID-19 Rebound
Symptomatic and virologic recrudescence after treatment of patients with COVID-19 with Paxlovid occurs in a tiny percentage of patients and generally is mild and self-limited.
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COVID-19: Duration of Shedding of Transmissible Virus
Patients with COVID-19 were found, by culture, to shed replication-competent virus after an initial PCR test for median durations of four to five days.