Clinical
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Predicting Coma Recovery in Critically Ill COVID-19 Patients
The COVID-19 pandemic presented us with an unprecedented number of critically ill patients with coma. These investigators determined that the degree of hypoxemia determined the depth and duration of coma, but recovery was much better than expected and could be delayed by several weeks.
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Treatment of Acute Vertigo
In a meta-analysis of published studies of treatment of acute vertigo, the authors concluded that treatment with an antihistamine is more effective than benzodiazepines for the acute symptoms. However, there was no difference between the two medications in terms of resolution within one week or within one month.
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Identifying and Treating Non-COVID Viral Respiratory Infections
Respiratory viruses are omnipresent and can cause a variety of clinical manifestations, from asymptomatic infections to life-threatening illnesses with multi-organ failure. About 25 million people visit their primary care physician every year with uncomplicated upper respiratory infections in the United States. Viral respiratory infections are recognized as key triggering factors in exacerbations of chronic respiratory diseases, such as bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD).
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Updated Tactics for Parkinson’s Disease Study Recruitment
Remote, decentralized studies allow for the recruitment of large, geographically dispersed cohorts from a single location. In considering whether to use a decentralized design or to include remote assessments, the research team must determine if these methods can adequately answer the question under study.
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How Should Researchers Proceed if They Suspect Neglect or Abuse?
If researchers interview a child during a minimal risk study at a school, and they suspect the child is a victim of abuse or neglect, investigators are ethically obligated to respond to this.
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Ethical Considerations for Trauma-Informed Care
Use the tenets of trauma-informed care by realizing the widespread effects of trauma; recognizing signs and symptoms; responding by including knowledge about trauma in policies, procedures, and practices; and avoiding retraumatization.
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Be Careful About Informed Consent if Pelvic Exams Happen While Patients Are Under Anesthesia
Incorporate explicit discussions with patients about pelvic exams conducted while patients are under anesthesia. These discussions should occur during consent processes for gynecologic procedures. Specifically, patients would be told about the potential for medical student involvement in these exams.
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Financial Conflicts Reported Inconsistently
It might be time to consider another approach to transparency on financial conflicts.
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The Trouble with Electronically Tracking Study Medications
Digital pills allow data to be recorded automatically about patients’ medication adherence, but patients and providers have expressed significant ethical concerns.
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Electronic Orders, Education Boost Requests for Ethics Consults
The electronic order is an important way to streamline ethics consultation requests, but additional, broader efforts will be needed.