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This article originally appeared in the September 2013 issue of Critical Care Alert.
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Most hospital-based clinicians are aware that anemia develops in many hospitalized patients.
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A popular field that is being discussed in medical research, in popular science, and by the media, epigenetics is broadly defined as the study of the changes in gene expression that occur on the DNA sequence and are heritable.
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In more than 12,000 patients at high risk of cardiovascular events, daily supplementation with 1 g of fish oil (85% eicosapentaenoic acid plus docosahexaenoic acid) did not reduce cardiovascular morbidity nor mortality over approximately 5 years of follow up.
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In an observational study conducted in Germany of more than 600 anemic cancer patients receiving parenteral iron (ferric carboxymaltose), hemoglobin levels were shown to rise significantly. The iron treatment was well tolerated. Randomized interventional studies are warranted to demonstrate efficacy in terms of physical function and quality of life and safety in this population.
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This paper details the result of a population-based cohort study of all Ontario, Canada, residents older than 66 years of age who began warfarin therapy for atrial fibrillation over an 11-year period. Patients were identified by the authors from data in the Ontario Health Insurance Plan.
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During family discussions, physicians who believe more strongly that life support should be withdrawn are more likely to present the option of comfort care and describe its benefits.
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Zolpidem, a commonly utilized agent for sleep disturbance, is associated with increased fall risk in hospitalized, non-pregnant, non-critically ill patients. Its use for a given patient and its appropriateness within standard order sets should be carefully considered.
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Special Report from the International Stroke Conference: Current Endovascular Interventions for Acute Ischemic Stroke Do Not Result in Better Clinical Outcomes than Intravenous Thrombolysis
