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Long-Term Maintenance Therapy After Percutaneous Coronary Intervention
An extended six-year follow-up of the HOST-EXAM study revealed the consistent benefit of the primary endpoint of fewer major cardiovascular events and less bleeding with clopidogrel vs. low-dose aspirin monotherapy in post-percutaneous coronary intervention patients who were on dual antiplatelet therapy for one year.
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How to Diagnose ATTR Cardiac Amyloidosis
A retrospective study of patients with confirmed cardiac amyloidosis showed negative light chain biomarkers and a typical pattern of cardiac amyloid on cardiac MRI was highly specific for the diagnosis of the transthyretin subtype and may obviate the need for further testing before starting treatment.
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ECMO-Supported CPR Disappoints for Treating Out-of-Hospital Cardiac Arrest
For patients with out-of-hospital cardiac arrest that was refractory to initial resuscitation efforts, adding extracorporeal membrane oxygenation to standard CPR did not result in a significant improvement in survival with favorable neurologic outcome.
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Surgical Risk of Mitral Valve Repair, Updated
A contemporary update of the Society of Thoracic Surgeons risk calculator for operative mortality and morbidity in nonemergent primary mitral valve repair for regurgitation shows an operative mortality rate of 1.2%, with a conversion to replacement of 6%, in more than 53,000 patients.
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Long-Term Air Pollution Exposure Could Raise Risk for Depression, Anxiety
Two research groups reported on breathing dirty air and how that affects mental health.
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A Comparison of Ceftaroline and Daptomycin in the Treatment of MRSA Bloodstream Infections
Ceftaroline is an acceptable alternative therapy for treatment of methicillin-resistant Staphylococcus aureus bacteremia.
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Role of Early VA-ECMO Implementation in Patients with Rapidly Deteriorating Severe Cardiogenic Shock
The ECMO-CS trial found that using early VA-ECMO in patients with rapidly deteriorating or severe cardiogenic shock (Society for Cardiovascular Angiography and Interventions stages D or E) did not result in better patient outcomes compared to initial conservative care.
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ICU Physician Wellness and Coping During the COVID-19 Pandemic
A binational, cross-sectional survey including 431 questionnaires assessing wellness and coping among physicians who worked in the intensive care unit during the COVID-19 pandemic found that physicians experienced moderate intrapandemic moral distress and burnout, yet also experienced moderate professional fulfillment.
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Home-Based STI Kits Can Help with Anal Cancer Screening
Anal cancer incidence has increased in recent years, and there are no consensus screening guidelines. Researchers found the use of home-based anal self-sampling kits improved screening.
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Adolescents Benefit from Dual Protection Messaging
Young people need multiple and diverse messaging about dual method use of contraception, according to a recent study. As researchers spent a decade working on an over-the-counter hormonal contraceptive pill, they also worked to address all the different aspects of this reality — including messaging for youths